Changing neighbours: remodelling of bone marrow stem cell niches during ageing and age-related myeloproliferative disorders

Relator: Dr. Simón Méndez-Ferrer, University of Cambridge (UK)

Dr. Méndez Ferrer is a group leader at the Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and a

Reader in Tranfusion Medicine at the Department of Haematology, University of Cambridge (UK).

His research focuses on the regulation of the environment (‘niche’) in which the blood stem cells reside both in health and disease. Blood stem cells are located in specialized niches which allow them to function according to the organism's requirements.

His group studies the mechanisms of how the stem cell niche fulfills these complex functions Through this, he aims to understand how the disruption of these mechanisms contributes to blood disorders.